"Institutionalism" (SAGE 2007) captured a good deal of the literature at the time it was published; however, there have been numerous excellent contributions to the literature since that time. These newer articles merit another readily-available collection,...
2012, SAGE Publications Ltd...
Book, Hardback, 3 items/volumes
Handbook of Computational Chemistry...
The role the Handbook of Computational Chemistry is threefold. It is primarily intended to be used as a guide that navigates the user through the plethora of computational methods currently in use; it explains their limitations and advantages; and it ...
2012, Springer Netherlands...
Book, Hardback, 3 items/volumes
Early years literacy research represents the foundation of literacy education, influencing the trajectory of literacy development as far as the high school years. This collection features key discussions and debates about the application of particular methods within the field,...
2011, SAGE Publications Ltd...
Book, Hardback, 4 items/volumes
Bresinsky, Andreas; Korner, Christian;...
This famous book on botany was published for the first time in 1894 by Eduard Strasburger and his co-workers. The present edition is based on a translation of the 36th edition of the German "Strasburger" and contains additional contributions by renowned experts in the field....
2012, Springer Berlin
Book, 2 items/volumes
One central and enduring image of the social science researcher is of an individual who commits a great deal of time to collecting original, primary data from a field of enquiry. This approach is often underpinned by a sincerely held belief that key research ...
2012, SAGE Publications Ltd...
Book, Hardback, 4 items/volumes
Encyclopedia of Sustainability ...
Sustainability in environmental usage refers to the potential longevity of vital human ecological support systems, such as the planet's climate system, systems of agriculture, industry, forestry, fisheries and the ocean, and fresh water, together with the impact of human communities,...
2012, Springer New York
eBook, Epublication "content package", Electronic book, 12 items/volumes
Dorband, Bernd; Muller, Henriette;...
Handbook of Optical Systems: Metrology ...
Metrology of Optical Components ...
Herbert Gross, born in 1955, joined Carl Zeiss in 1982 after finishing his physics degree as specialist for optical design. Since 1995 he has been working as head of the department of optical design, while also teaching as a lecturer in Aalen and Lausanne. The new handbook is an intuitive,...
2012, Wiley-VCH
Book, Hardback
Critical and Primary Sources
Textiles: Critical and Primary Sources is a major multi-volume reference work that draws together 93 seminal texts on textiles. Textile culture stretches geographic, historical, methodological and disciplinary boundaries, and defies chronological ordering....
2012, A & C Black Publishers ...
Book, Quantity pack, 4 items/volumes
Islamic Philosophy, Science, Culture,...
Studies in Honor of Dimitri Gutas
Islamic intellectual thought is at the center of this collection of articles honoring Dimitri Gutas by friends, colleagues, and former students. The essays cover three main areas: the classical heritage and Islamic culture; classical Arabic science and philosophy;...
2011, Brill
Book, Hardback
Modern Crop Protection Compounds
This one-stop reference for everyone working in the agrochemical business is the leading reference in the field, with first-class authors from all major crop protection companies, including Bayer, Dow, Syngenta and BASF. In three volumes, one each on herbicides, fungicides and insecticides,...
2011, Wiley-VCH
Book, Hardback, 3 items/volumes
Oxford Dictionaries
The Oxford Latin Dictionary is the world's most authoritative dictionary of classical Latin, with comprehensive coverage of the language from its beginnings until AD 200. More than fifty years in the making, and originally published in a series of fascicles (parts) from 1968,...
2012, Oxford University ...
Book, Hardback
![[Set of Handbook and Bibliography]](/annot/426F6F6B446174617C7C393738333131303237323732377C7C434F50.jpg?sq=1 "Villars, Pierre; Cenzual, Karin; Penzo, Marinella")
Villars, Pierre; Cenzual, Karin;...
[Set of Handbook and Bibliography]
Since the discovery of X-ray diffraction in 1913 over 100.000 different inorganic substances (also called compounds or phases) have been structurally characterized. The information has been published in over 72.000 publications spread over 1.000 different scientific journals....
2011, de Gruyter
Book, Hardback, 3 items/volumes
Risk has become one of the main topics in fields as diverse as engineering, medicine and economics, and it is also studied by social scientists and psychologists. But the topic of Risk also leads to more fundamental questions such as: What is Risk? What can decision theory contribute to the analysis of Risk?...
2012, Springer Netherlands...
Book, Hardback, 2 items/volumes
Chen, Harold
Atlas of Genetic Diagnosis and ...
Dr. Chen shares his almost 40 years of clinical genetics practice in a comprehensive pictorial atlas of almost 250 genetic disorders, malformations, and malformation syndromes. The author provides a detailed outline for each disorder, describing its genetics, basic defects,...
2011, Springer, Berlin
Book, Hardback, 3 items/volumes
Collection: Power and Organizations ...
Power theory, as a burgeoning field of study, has had, and continues to have, a huge impact across the social sciences. In particular, there has been considerable innovative work in the fields of organization studies and politics which in turn has fed research in a wide array of related fields,...
2012, SAGE Publications Ltd...
Book, Hardback, 8 items/volumes
Reports of Overseas Private Investment ...
This comprehensive two-volume work is a collection of determinations from OPIC, the US governmental political risk insurance provider, in the form of its Memoranda of Determinations from 1966 through to 2010. An important part of international investment ...
2011, Oxford University ...
Book, Hardback, 2 items/volumes
Berghaus, Gunter; Berghaus, G Nter
International Futurism 1945-2009
A Bibliographic Handbook
Dieser Band enthält eine umfassende bibliographische Aufbereitung von über 25.000 Publikationen und ist als Orientierunghilfe konzipiert für Studenten und Forscher, die Monogaphien und Aufsätze zu den bedeutensten Künstlern und Literaten der futuristischen Kunstbewegung suchen....
2012, de Gruyter
Book, Hardback
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Drug Delivery in Oncology
From Basic Research to Cancer Therapy
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Bibliographic data: Publisher: Wiley-VCH published in: Weinheim, DE ISBN: 978-3-527-32823-9 Pages: 1822 Language: German (de) Size: Width [176 mm] Height [245 mm] Depth [88 mm] Weight: 3888 gram Product Type: Book Binding: Hardback, 3 items/volumes Publication Year: 2011
Please ask for a special offer 6D656E672E6B697440646965746D61726472656965722E64656D656E672E6B697440646965746D61726472656965722E6465
Last Update: 04/12/2012 20:37:13 |
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In this first authoritative overview on modern cancer chemotherapy 121 international specialists have contributed their experience and recent data for what is likely to become the gold standard in the field.
The authors summarize knowledge gained over the past decade, from basic concepts to successful applications in the clinic, covering active and passive targeting strategies as well as tissue-specific approaches. All current and future targeted delivery systems are discussed, from ligand-based to antibody-based polymer-based systems, right up to micro- and nanoparticulate systems. A special section covers the delivery of nucleic acid therapeutics, such as siRNA, miRNA and antisense nucleotides. In each case, a description of the basic technique is followed by a discussion of the latest preclinical and clinical developments in the field. By virtue of its clear and didactic structure, rich illustrative material and summary chapters, this handbook and ready reference enables the efficient transfer of knowledge between different disciplines, from basic research to the clinician and vice versa. It is equally well suited for professionals, researchers and students in medical oncology and cancer biology, and is also excellent for teaching medical students the foundations of 21st century cancer chemotherapy. In this first authoritative overview on modern cancer chemotherapy 121 international specialists have contributed their experience and recent data for what is likely to become the gold standard in the field. The authors summarize knowledge gained over the past decade, from basic concepts to successful applications in the clinic, covering active and passive targeting strategies as well as tissue-specific approaches. All current and future targeted delivery systems are discussed, from ligand-based to antibody-based polymer-based systems, right up to micro- and nanoparticulate systems. A special section covers the delivery of nucleic acid therapeutics, such as siRNA, miRNA and antisense nucleotides. In each case, a description of the basic technique is followed by a discussion of the latest preclinical and clinical developments in the field. By virtue of its clear and didactic structure, rich illustrative material and summary chapters, this handbook and ready reference enables the efficient transfer of knowledge between different disciplines, from basic research to the clinician and vice versa. It is equally well suited for professionals, researchers and students in medical oncology and cancer biology, and is also excellent for teaching medical students the foundations of 21st century cancer chemotherapy.
Table of Content PRINCIPLES OF TUMOR TARGETING Limits of Conventional Cancer Chemotherapy Pathophysiological and Vascular Characteristics of Tumors in Relation to Drug Delivery The EPR-Effect in Relation to Tumor Targeting Pharmacokinetics of Antibodies and Albumin: Implications for the Role of the MHC Receptor FcRn and T Cell Receptor for the Design of Drug Delivery Systems Development of Cancer Targeting Ligands and Ligand-Drug Conjugates Two-Step Approaches to Cancer Therapy TUMOR IMAGING Imaging Techniques in Drug Development and Clinical Practice Magnetic Nanoparticles in MR Imaging and Drug Delivery Near Infrared Imaging Imaging Techniques for Cancer - From Microscopy to Quantum Dots and Nanoshells Preclinical and Clinical Tumor Imaging with PET and SPECT/CT MACROMOLECULAR DRUG DELIVERY SYSTEMS Antibody-Based Systems Empowered Antibodies for Cancer Therapy Vascular Targeting to Penetrate Solid Tumors Considerations of Linker Technologies Clinical Experience with Maytansine Antibody Conjugates Mylotarg and Beyond Antibodies for the Delivery of Radionuclides Bispecific Antibodies and Immune Therapy Targeting POLYMER-BASED SYSTEMS Design of Polymer-Drug Conjugates Dendritic Polymers as Drug Delivery Systems in Oncology Self-Immolative Systems Ligand-Assisted Targeting of Polymer Therapeutics Drug Conjugates with Poly(ethylene)glycole Thermally Responsive Polymers Polysaccharide-Based Drug Conjugates for Tumor Targeting Serum Proteins as Drug Carriers of Anticancer Agents Combination Therapy with Drug Polymer Conjugates Clinical Experience with Drug Polymer Conjugates NANO- AND MICROPARTICULATE DRUG DELIVERY SYSTEMS Nanocarriers as Delivery Systems The Development of Pegylated Liposomes Immunoliposomes Responsive Liposomes (for Solid Tumor Therapy) Liposomal Formulations for Optimized Combination Therapy POLYMER-BASED SYSTEMS Micellar Strcutures as Drug Delivery Systems Tailor-Made Hydrogels for Tumor Delivery pH-Triggered Micelles Albumin Nanoparticles Carbon Nanotubes LIGAND-BASED DRUG DELIVERY SYSTEMS Cell-Penetrating Peptides in Cancer Targeting Subcellular Targeting Targeting to Peptide Receptors Aptamer Conjugates Design and Synthesis of Drug Conjugates of Vitamins and Growth Factors Drug Conjugates with Fatty Acids SPECIAL TOPICS RNA Drug Delivery Approaches Local Gene Delivery for Therapy of Solid Tumors RNA Delivery Using Viral Vectors Design of Targeted Protein Toxins CNS Drug Delivery Liver Tumor Targeting Drug Delivery in Photodynamic Therapy Tumor Targeting Strategies with Anticancer Platinum Complexes |
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